The ingredients of Wire-2-Wire, including CoQ10, work together to help keep your horse at its best. One of the major effects is the increased antioxidant capacity that allows the horse to remove the damaging effects of a strenuous workout and reduce harmful by-products produced by its environment.
Wire-2-Wire leads to better heart health, helps control cholesterol, boosts testosterone, helps prevent diabetes, improves the immune system and delays aging, which increases energy and allows the horse athleticism to control the event outcome.
“Our vision is to improve the quality of horse training by the use of our product. Audacious? Yes. Impossible? A lot of people once thought voices over telephone wires, light without fire, microbes that cure diseases and robots roving Mars were "impossible," yet they're all old news today. An audacity of imagination combined with the power of science makes the "impossible" possible every day.”
- PVG, Jr.
According to the CHRB Rulebook and the FEI Equine Prohibited List everything in this blend is legal for equine use and currently available in some form for legal sale. The difference is the synergistic blend of pharmaceutical grade ingredients and dosing. Most components are included for general well-being such as vitamins B1, B2, B3, B5, B6, B12, C, D & E, Biotin, Beta Carotene, Calcium, Zinc, Selenium and Iron.
Dosing was chosen to match the recommendations of the National Research Council (NRC) requirements for working horses. Also included are amino acids, particularly the branched chain amino acids designed for prevention of muscle breakdown during exercise. Other common components are Glucosamine & Methylsulfonylmethane (MSM) which maintain general joint health.
It is well known that glutathione is an essential cellular radical protectant (i.e., prevents cell damage due to exercise, pollutants, etc.) that becomes depleted upon extreme exertion. Natural glutathione is not well-absorbed in the diet. However, glutathione is made in the body by converting N-acetyl-Cysteine (NAC) into glutathone. NAC is absorbed well in the diet which promotes cellular biogenesis of glutathione.
Lipoic Acid is required for mitochondrial energy production as well as amino acid metabolism. It also has been shown to reduce inflammation and helps vitamin E and coenzyme Q and glutathione do their functions more effectively.
Echinacea root has been shown in studies to increase both white and red blood cell counts. This is intended to help improve oxygen use and immune system. In cases where anti-inflammatory medications are also used, this may help rescue low red blood cell counts.
The last, and most important component, is CoQ10. This leads to many positive effects. It is important for electron transport chain function in mitochondria, acts as an antioxidant that leads to better cardiovascular health (optimal blood pressure), increases energy/ athleticism, helps to control cholesterol levels, and extends lifespans.
Additionally, it helps to regulate blood glucose levels which improves or prevents laminitis. It also has positive effects on the immune system and improves skin and gums. Another outcome that would be of more benefit for studding horses is that it appears to increase fertility. Some studies have indicated a boost in testosterone. The levels used in Wire-2-Wire are safely tolerated. Although no studies have been done, it would make sense that this may lessen the need for bute or banamin over time.